Maxipime cefepime hydrochloride, usp for injection for. Maxipime cefepime hydrochloride, usp for injection for intravenous or intramuscular use to reduce the development of drugresistant bacteria and maintain the effectiveness of maxipime and other antibacterial drugs, maxipime should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. Maxipime in the dry state in original cartons should be stored at less than 25oc. Cefepime dosing regimens in critically ill patients receiving. In fact, even normal dosages can cause overdose symptoms in people with kidney disease. In individuals with risk factors for cefepime neurotoxicity, such as renal. Cefepime neurotoxicity american college of clinical pharmacy. Maxipime definition of maxipime by the free dictionary. The pharmacokinetics of cefepime are unaltered in patients with impaired hepatic function who received a single 1g dose. Dailymed aztreonam injection, powder, lyophilized, for. Guidelines recommend cefepime plus vancomycin, gentamicin, and rifampin if prosthetic material is present for culturenegative nosocomial endocarditis associated with vascular cannulae or early less than 1 year after surgery prosthetic valve endocarditis.
Maxipime cefepime hydrochloride injection, powder, for. Maxipime uses maxipime may be given to adults or children as young as two months old to treat certain types of bacterial infections, such as pneumonia, urinary tract infections, or skin infections. Maxipime should be administered at the same time each day and following the completion of hemodialysis on hemodialysis days see table 2. Cefepime dosing regimens from available drug dosing rec ommendations. Information on cefepime marketed as maxipime share. Each scored white tablet contains 100 mg allopurinol and the inactive ingredients lactose, magnesium stearate, potato starch, and povidone. Maxipime fda prescribing information, side effects and uses. The dosage of maxipime for hemodialysis patients is 1 g on day 1 followed by 500 mg every 24 hours for the treatment of all infections except febrile neutropenia, which is 1 g every 24 hours. Cefepime is a cephalosporin antibacterial drug used to treat pneumonia, urinary tract, skin, and intraabdominal infections. Maxipime synonyms, maxipime pronunciation, maxipime translation, english dictionary definition of maxipime. Maxipime for injection is supplied for intramuscular or intravenous administration in strengths equivalent to 500 mg, 1 g, and 2 g of cefepime. This leaflet does not contain all the information about maxipime. The information in this leaflet answers some questions you may have about maxipime. A package insert is a document included in the package of a medication that provides information about that drug and its use.
Careful dosage adjustment and a high index of suspicion are essential in this population. Clavulanic acid and its salts is an inhibitor of the enzyme betalacatamase which, produced by bacteria, could inhibit the activities of beta lactam antibiotics like cefixime. A broadspectrum cephalosporin antibiotic, c19h24n6o5s2, used in its hydrochloride form to treat a variety of infections, including skin and urinary. Zyloprim allopurinol has the following structural formula. Maxipime cefepime hydrochloride this product information is intended only for residents of the united states. Due to the unprecedented nature of the covid19 pandemic, anyone reporting an adverse event andor a product complaint via phone, should you receive a network busy signal ie. Maxipime 2 g injection composition maxipime cefepime hydrochloride for injection is a cephalosporin antibiotic intended for intramuscular or intravenous administration. It is effective against both, gram positive and gram negative bacteria. The larginine, at an approximate concentration of 707 mgg of cefepime, is added to control the ph of the constituted.
Highlights of prescribing information age group dosage. Maxipime cefepime hydrochloride for injection, for intravenous or intramuscular. In this indication it is essential that metrodinazole also be administered. Cefepime maxipime side effects, dosage, interactions. Insert piercing pin of administration set into port with a twisting motion until the pin is firmly seated.
There are also occasions where a person might use maxipime for offlabel unapproved purposes, such as to treat infections that are not considered. Highlights of prescribing information these highlights do not include all the information needed to use cubicin safely and effectively. Cefepime is licensed for adults and children as young as two months old with certain bacterial infections. Subcutaneous administration of cefepime journal of pain and. The following is the supplementary data to this article. Side effects of maxipime cefepime hydrochloride for injection. Package inserts for prescription drugs often include a separate document called a patient package insert with information written in. Patients treated with cubicin were 69% male and 31% female. Zyloprim is known chemically as 1,5dihydro4hpyrazolo 3,4dpyrimidin4one. Cefepime is a cephalosporin sef a low spor in antibiotic.
It contains the equivalent of not less than 90 percent and not more than. Pharmacokinetics, cefepime, goats, intravenous, intramuscular. Dates of starting and stopping cefepime therapy, along with dosage of the. Maxipime cefepime hydrochloride, usp for injection fda. Medical calculators for the clinician, comprehensive guide to drug therapy, intravenous iv drug dilution, dosing calculators, nutrition and diet calculators. The global acceptability was strongly agreeable with all the subjects. The related drug information index provides comprehensive access to all drug information related to a specific drug types of content include full prescribing information, drug summaries, full prescribing information continuing medication education full pi cme, medication guides, risk evaluation and mitigation strategies rems summaries, rems continuing medication education rems cme, and. Cefepime is the generic form of the brandname drug maxipime, which is used to treat bacterial infections such as urinary tract infections, pneumonia, and skin infections. Maxipime is a sterile dry mixture of cefepime hydrochloride and larginine. Maxipime cefepime seffehpeem consumer medicine information what is in this leaflet the medicine which your doctor has prescribed for you is called maxipime. Maxipime injection is used to treat bacterial infections in many different parts of the body. Cefepime injection is used to treat many kinds of bacterial infections, including severe or lifethreatening forms. It belongs to the class of medicines known as cephalosporin antibiotics. Single 30minute intravenous infusions of 500 mg, 1 g and 2 g doses of aztreonam for injection in healthy subjects produced aztreonam peak serum levels of 54 mcgml, 90 mcgml and 204 mcgml, respectively, immediately after administration.
Zyloprim is known chemically as 1,5dihydro4 hpyrazolo 3,4dpyrimidin4one. Find medication information including related drug classes, side effects, patient statistics and answers to frequently asked questions. Although dosage adjustment is recommended for patients with renal. Subcutaneous infusion of cefepime appeared to result in a. Globalrph medical calculators, clinicians guide to drug. However, this medicine will not work for colds, flu, or other virus infections. Maxipime is a sterile, dry mixture of cefepime hydrochloride and larginine. The serum drug concentrationtime profile was characteristic of a 2 and. Cefepime has an extended spectrum of activity against grampositive and gramnegative bacteria, with greater activity against both types of organism than thirdgeneration agents. Maxipime is indicated in paediatric patients over 2 months of age for the treatment of the.
For prescription medications, the insert is technical, providing information for medical professionals about how to prescribe the drug. Cefepime is a fourthgeneration cephalosporin antibiotic. Maxipime contains cefepime as an active substance and belongs to the fourth generation of cephalosporins. Cefepime may also be used for purposes not listed in this medication guide. Maxipime is a cephalosporin antibacterial indicated for the treatment of the following infections caused by susceptible strains of the designated microorganisms. Cefixime is an oral thirdgeneration cephalosporin antibiotic used for primarily upper respiratory infecions.
Maxipime is a broad spectrum antibiotic and exerts bactericidal effects by inhibiting bacterial cell wall synthesis. A maxipime overdose is more likely to cause problems in people who have poorly functioning kidneys, as the kidneys remove this medication from the body. Single dose pharmacokinetics of cefepime after intravenous and. Maxipime cefepime dosing, indications, interactions. Feraheme is contraindicated in patients with known hypersensitivity to feraheme or any of its components.
It is administered intravenously through a vein or by injection into a. Maxipime cefepime hydrochloride injection, powder, for solution hospira, inc highlights of prescribing information these highlights do not include all the information needed to use maxipime safely and effectively. Maxipime patient information including if i miss a dose. Easy to read fda package insert, drug facts, dosage and administration, and adverse effects for dilantin phenytoin. It works by killing bacteria or preventing their growth. If your healthcare provider recommends this drug, you may be wondering who makes cefepime and whether there is a generic version.
Table 3, and the package insert should be consulted. Maxipime injection may also be used for purposes not listed in this medication guide. Maxipime cefepime hydrochloride for injection side. It is a xanthine oxidase inhibitor which is administered orally. Call your doctor for instructions if you miss a dose of cefepime. Select how to get your meds and pay online to save. Seek emergency medical attention or call the poison help line at 18002221222. Maxipime powder for solution for injection drug summary. A maxipime vial contains 500 mg, 1g or 2g of cefepime activity in the form of a sterile mix of cefepime dihydrochloride monohydrate and larginine. This emedtv page explores this topic, including a list of some offlabel unapproved uses for cefepime and an explanation on how the drug works.
Biochemicals, cefepime, histopathology, nephrotoxicity, rats. Maxipime cefepime hydrochloride, usp is a semisynthetic, broad spectrum, cephalosporin antibiotic for parenteral administration. Find its price or cost, dose, when to use, how to use, side effects, adverse effects, substitutes. A 2007 metaanalysis suggested when data of trials were combined, mortality was increased in people treated with cefepime compared with other. Refer to full directions on administration set carton prior to use. Our maxipime side effects drug center provides a comprehensive view of available drug information. Maxipime and other antibacterial drugs, maxipime should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
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